Genomics and Bioinformatics (Ch-3) Class XII (Very Short Questions)

GENOMICS AND BIOINFORMATICS

(1 Mark Questions)

1. Why is a DNA sequence always listed in the direction 5’to 3′?
2. What are ESTs? How are they useful in genome analysis?
3. How can SNPs be used to predict susceptibility to diseases?
4. Proteome of a given cell is dynamic. Why?
5. When aligning two or more genetic sequences, it is sometimes necessary to insert gaps, why?
6. Why there is a need to create bioinformatics databases?
7. Name a disease caused due to single gene mutation.
8. Indicate which one of the two broad areas of genomics addresses the biological functions of genes.
9. Human population vary greatly in their susceptibility to diseases. Why?
10. Which were the two first genomes to be sequenced? Name the organization which achieved this feat.
11. Suppose you are a planning a large scale hybridization programme in maize. How can this task be made less labour intensive?
12. In DNA sequence readouts occasionally a S symbol appears. What does this means?
13. What are ESTs? How are they useful in genome analysis?
14. Who is curator? What is curation?
15. Name the database which was created to manage to redundancy in ESTs.